Assignment 

 Statistical Analysis of a Clinical Question

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DNP Biostatistics Assignment: Statistical Analysis of a Clinical Question

Objective:
To apply biostatistical methods to a real-world clinical question relevant to advanced nursing practice.

Instructions:

Part 1: Define Your Clinical Question (PICO Format)
Develop a clearly defined clinical question using the PICO format (Population, Intervention, Comparison, Outcome).
Example: In adult patients with hypertension (P), how does a nurse-led lifestyle intervention (I) compared to usual care (C) affect blood pressure levels (O)?

Part 2: Select a Dataset
Use one of the following:

·        A publicly available health dataset (e.g., CDC, NHANES, WHO)

·        Simulated data provided by the instructor

·        De-identified clinical data with appropriate IRB clearance

Part 3: Perform Descriptive Analysis

·        Summarize key demographic variables

·        Report measures of central tendency (mean, median) and variability (standard deviation, range)

·        Create at least 2 visualizations (e.g., histogram, box plot, bar chart)

Part 4: Conduct Inferential Analysis
Choose an appropriate statistical test to answer your clinical question:

·        T-test, chi-square, ANOVA, correlation, linear/logistic regression, etc.

·        Justify your choice of test

·        Report the test statistic, p-value, and interpret the result

Part 5: Interpretation and Clinical Relevance
Write a brief discussion (300–500 words) explaining:

·        What the statistical findings mean in the context of your clinical question

·        Implications for nursing practice or healthcare decision-making

Deliverables:

·        Typed report (5–7 pages), including tables/figures

·        Appendix with code/output (if using statistical software like SPSS, R, or Excel

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